Universal 10-minute cancer test in sight
Scientists have created an experimental test that can detect cancer in less than 10 minutes. The test uses a DNA feature that seems to be common to all types of cancer and does not occur in healthy tissue.
Study finds that various cancers share the same ‘DNA signature.’
A team at the University of Queensland in Australia has discovered that DNA fragments from cancer cells adopt a unique structure in water.
The researchers uncovered the same “DNA signature” in samples of breast, prostate, and bowel cancer tissue as well as in lymphomas.
From these results, they developed a test that can detect the apparently universal cancer DNA signature in less than 10 minutes.
They also demonstrated that the test was up to 90 percent accurate over 200 samples of tissue and blood.
Higher accuracy in a test means that it produces fewer false positives, which are results that suggest that cancer is present when it is not.
The journal Nature Communications has now published a study paper about the test and how the scientists developed it.
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The technology behind the test is “very accessible and inexpensive,” he adds, and it “does not require complicated lab-based equipment like DNA sequencing.”
The scientists investigated the DNA that cells shed when they die. This “circulating free DNA” is always present in tissues and blood because cells die and renew all the time.
The idea of using circulating free DNA as a diagnostic tool for cancer is not new. Scientists have been looking for a cancer signature in this DNA for a while.